Midwives may independently prescribe, order and administer this drug.
An oral antibiotic of the cephalosporin class, related to penicillin.
Indications and Clinical Use:
For use as a second line treatment of urinary tract infections in pregnancy and postpartum. Prescribe only when there is no alternative. This drug has an extended spectrum of activity including about 95% coverage of Escherichia coli.
Allergy to cephalosporin group of antibiotics
Warnings and Precautions:
Chance of cross-reactivity is low (around 3%) if the patient is penicillin sensitive, however do not use it for highly allergic (e.g. anaphylactic) patients. Use with caution in patients with colitis.
Category L2 – Limited Data – Probably Compatible
Diarrhea, gas, loose stools, nausea and stomach upset.
Dosage and Administration:
Cystitis: 400mg PO once daily (OD) for 7 days.
Onset of Action:
Time to peak, serum: 2-6 hours; delayed with food.