Antibiotics for Chlamydia Trachomatis

Doxycycline and Aazithromycin are first choice treatments however Doxycycline is not to be used during pregnancy. During pregnancy and lactation, treatments of choice are Amoxicillin, Azithromycin or Erythromycin.

Amoxicillin (Amoxil®, Polymox®, Trimox®),
Azithromycin (Zithromax®)
Erythromycin
Doxycycline

Chlamydia Trachomatis is a reportable infection and is the most common bacterial sexually transmitted infection in Canada. Chlamydia Trachomatis infection is commonly undiagnosed unless screened for as the majority of infected individuals are asymptomatic. Screening during pregnancy should occur at the first prenatal visit and if positive, a test of cure is required at 3-4 weeks post antibiotic completion of treatment for pregnant and/or breastfeeding clients. Timely treatment reduces the risk of symptomatic infection with its associated risks. Repeat screening is recommended at 6 months if client is at high risk of re-infection. Partners also need to be informed, and advised to see their health care provider for assessment, screening and treatment. Untreated Chlamydia Trachomatis can be associated with intestinal symptoms, mucopurulent cervicitis, increased vaginal discharge with or without odour, conjunctivitis in neonates and pneumonia in infants less than 6 months of age. Major sequelae may cause pelvic inflammatory disease, ectopic pregnancy, infertility, chronic pelvic pain and Reiter Syndrome.

Amoxicillin (Amoxil®, Polymox®, Trimox®) STI Treatment