Hepatitis B immune globulin

Revised March 4, 2019

Section 1.1

Midwives may independently prescribe, order and administer this drug.

HBIg is a solvent detergent treated, fractionated human blood product that provides immediate, short-term protection against hepatitis B infection.

Indications and Clinical Use:

HBIg should be given immediately after birth to any infant born to either an HBsAg positive woman or woman at high risk for hepatitis B infection (i.e. intravenous drug user or sex trade worker) whose infection status in unknown or negative.

Dosage and Administration:

Infant: 0.5 mL IM immediately after birth, along with first dose of hepatitis B vaccine series Ensure the vaccine is given at the same time as HBIg but in a separate syringe and at a separate injection site.