Hepatitis B Vaccine

Revised December 11, 2017

Section 1.1

Midwives may independently prescribe, order and administer this drug.

(HyperHep®, BayHep®, Infanrix hexa®, Engerix-B®, Recombivax HB®) is administered to the infants of HBsAg positive individuals, or when otherwise indicated, within 24 hours of the birth. Subsequent doses of Hepatitis B vaccine are included in Infanrix hexa® which is given with the normal 2, 4 and 6 month immunizations as per BC Centre for Disease Control guidelines. Infants requiring hepatitis B vaccination at birth will receive a total of four doses of vaccine. Whenever vaccines are administered, the midwife must send a record of immunization to the physician or primary care nurse practitioner to whom care is transferred at 6 weeks postpartum.

Indications and Clinical Use:

Hepatitis B vaccine should be given to the newborn at birth if any of the following risk factors apply:

  1. If client is known to be HBsAG positive or at high risk (e.g. IV drug user and/or sex trade worker) for hepatitis B, but negative (possible window period) or unknown for HBsAG
  2. If client is at high risk for hepatitis B other than IV drug user and sex trade worker and status is unknown or negative
  3. Primary caregiver or other household contact of infant has chronic hepatitis B virus infection
  4. If other primary caregiver is at high risk for hepatitis B and their status is unknown or negative

Dosage and Administration (Newborns):

Give 1 dose hepatitis B vaccine (0.5 ml IM) immediately after birth

If HBIg indicated, ensure vaccine is given at the same time but in a separate syringe and at a separate sites.