Miconazole (Monistat®)

Section 1.1

Midwives may independently prescribe, order and administer this drug.

Anti-fungal agent which inhibits biosynthesis. This causes damage to the fungal cell wall membrane and increases permeability.

Indications and Clinical Use:

For the treatment of vulvovaginal candidiasis and other fungal skin and mucous membrane infections.


Hypersensitivity to Miconazole or any component of the formulation.

Warnings and Precautions:

Avoid contact with eyes when using topical formulation.
Discontinue use if sensitivity or irritation occurs.
Any excess cream or ointment should be removed from the nipples before nursing.




Category L2 – No Human Data – Probably Compatible

Miconazole has poor oral bioavailability and unlikely to adversely affect the breastfed newborns, including topical application to the nipples.

Adverse Reactions:

Allergic dermatitis, burning, maceration, irritation and itching.

Dosage and Administration:

Topical or Intravaginal.

  • Monistat® 7 cream: 15 g applicator-full intravaginally once daily at bedtime for 7 consecutive days.
  • Monistat® 7 vaginal suppositories: 1 (100 mg) suppository intravaginally daily at bedtime for 7 consecutive days.
  • Monistat® derm cream: Apply a thin layer of cream topically to cover the affected area twice daily. Continue treatment for 2 weeks.
  • Monistat® 3 vaginal ovules: 1 (400 mg) ovule intravaginally daily at bedtime for 3 consecutive days.